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RetroVirox Inc.

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Business Name:
RetroVirox Inc.
Business Genre:
Business Description:

Biotechnology company especializing in antiviral assays and cell-based screening for antiviral compounds [2]

Website:
https://retrovirox.com/RetroVirox_-_The_Antiviral_Testing_CRO.html
City:
San Diego
State:
CA
Country:
USA
Data/Evidence of Effectiveness:
The company offers several neutralization in vitro assays and now offers SARS-CoV-2 pseudoviruses that can be used to test vaccines [6]. No data was found
Complimentary Products Needed to Perform Test:
N/A
Setting of Care:
N/A
Current Status / Clinical Development Stage / Expected Milestones:
The company is “optimizing assays against the live infectious SARS-CoV-2” [4]. V9
Funding & Ownership :
Privately; Last funding type was a grant; Estimated revenue $1-10M [1-2]
Business Model:
The company offers a number of AAV neutralization assays including one for Influenza [5]
IP:
proprietary product pipeline of novel small-molecules with antiviral and immunomodulatory properties [3]
History & Origins :
“RetroVirox was founded with an initial investment by scientists and entrepreneurs to translate into cures research previously funded by the National Institutes of Health (NIH)” [2]
Date EUA Issued:
N/A
Sources:
[1] https://www.crunchbase.com/organization/retrovirox; [2] https://retrovirox.com/ABOUT_US.html; [3]https://retrovirox.com/Pipeline.html; [4] https://retrovirox.com/Coronavirus_Antiviral_Services_-_RetroVirox,_Inc..html [5]https://retrovirox.com/AAV_Neutralization_Assays_-_RetroVirox,_Inc..html [6] https://www.retrovirox.com/News/Entries/2020/3/17_RetroVirox_Launches_Coronavirus_Assays_to_Evaluate_COVID-19_Vaccines_and_Therapeutics.html
Organization:
Juan Lama, PhD (Chief Scientific Officer), Isabel Cisneros (Program Manager) [2]
Time to Result:
N/A
Test Sample Type:
N/A
Technology Overview:
The assay uses “HIV pseudoviruses coated with the viral spike (S) protein of SARS-CoV-2 (Wuhan isolate)” that can be used to determine “neutralizing activity of therapeutic antibodies”, “test experimental COVID-19 vaccines” and “evaluate small-molecule entry inhibitors targeting the S viral protein, the ACE-2 viral receptor, or host proteases and other targets involved in SARS-CoV-2 viral entry” [4]
Testing Type:
N/A
Test Category:
Other
Test Name:
SARS-CoV-2 Pseudovirus assay for Neutralizing Antibodies
Clinical Application & Need:
future prevention/ treatment

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