NONPROFIT, NONPARTISAN PLATFORM OF ACCURATE SCIENCE-BASED SOLUTIONS TO COVID-19

What Therapies hold promise for Covid-19?

In this section we highlight what we believe are among the most promising therapies being offered today.  Members should submit advancements for review and possible inclusion in this section.  SUBMIT


INNOVATIVE THERAPIES THAT SHOW PROMISE

MATH+ PROTOCOL

The MATH+ Hospital Treatment Protocol for COVID-19 is intended for use in the hospitalized patient, with an emphasis on early initiation — as soon as the patient develops a need for supplemental oxygen.  MATH+ hospitals have been reporting hospital mortality between 4% and 10%  as opposed to approximately 23%.  MORE >

OUTPATIENT (HOME) THERAPY

A paper authored by 23 physicians concludes  that it is conceivable that some if not a majority of hospitalizations could be avoided with a treat-at-home first approach with appropriate telemedicine monitoring and access to oxygen and therapeutics. An algorithm based on age and comorbidities that enables monitoring and treated at home during self-isolation to reduce risks of hospitalization and death. MORE > 

BELOIT PROTOCOL

At a single institution, consecutive case series of 25 COVID-19 hospitalized patients treated with as adjuvant therapy.  All 25 patients in the series survived hospitalized COVID-19 without mechanical ventilation or renal replacement therapy (RRT) and were discharged on room air within a median of 3 days (range 1-16 days).  In this series, combined treatment with in an adjuvant setting was associated with 100% survival and improved radiographic outcomes, as well as statistically significant improvements in clinical, biomarker, and renal function measurements. The 9 patients with extremely high LDH (>365, Wuhan model prediction of 98% mortality) survived and were discharged on room air.  MORE >

NOTE: Additional information about each is available for members only who have signed agreement regarding use and distribution of information.  


Therapies for treat COVID-19 can be placed into two broad categories:

• Therapeutics that treat viral infection.
• Therapeutics that mitigate COVID-19 complications and/or comorbid conditions.

FasterCures, a center of the Milken Institute, is currently tracking the development of treatments and vaccines for COVID-19 (coronavirus). This tracker contains an aggregation of publicly-available information from validated sources.

According to Milken there are: 316 Treatments in 7 categories are being developed now.

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