Dr. Christopher Schaber, President and CEO of Soligenix, a company developing drug therapies in rare diseases and areas of unmet medical need, including a treatment for oral mucositis in head and neck cancer patients. Chris, your drug, Dusquetide or SGX942, sounds like a tremendous development. Can you tell us more about it? Christopher Schaber: We believe Dusquetide is an important development, and we will be announcing any day that we will be initiating the Phase 3 pivotal study and opening it up for enrollment. We will now have two pivotal Phase 3 clinical trials actively enrolling patients. The other I…
Author: Alexandra Barnes
CEL-SCI Corporation recently announced that no further patient enrollment is required in the pivotal Phase 3 head and neck cancer study of its investigational immunotherapy, Multikine. The accrual and treatment phases of this Phase 3 study are complete. 928 patients are enrolled in the study, and are being followed-up as required by the study protocol. In addition, the company also recently announced that the study’s Independent Data Monitoring Committee (IDMC) completed its most recent review of the data from all 928 patients enrolled in the study, and recommended continuing the study as there was no evidence of any significant safety questions.…
Novocure is an oncology company working to develop a novel cancer treatment utilizing a proprietary therapy called Tumor Treating Fields, the use of electric fields tuned to specific frequencies to disrupt solid tumor cancer cell division. Novocure’s commercialized product is approved for the treatment of adult patients with glioblastoma. The device, Optune, is a portable, non-invasive medical device designed for continuous use throughout the day by the patient. The device has been shown in in vitro and in vivo studies to slow and reverse tumor growth by inhibiting mitosis, the process by which cells divide and replicate. The Optune device…
TapImmune Inc., a Florida-based leading clinical-stage immuno-oncology company recently announced that it has enrolled the final patient in a randomized Phase 2 clinical study of its novel T-cell vaccine candidate TPIV200 for treating triple-negative breast cancer (TNBC). This study is designed to help determine the optimal vaccine dose and regimen to maximize the immune response generated against the vaccine’s molecular target, folate receptor-alpha (FRa). FRa is a cancer cell biomarker that is highly correlated with disease recurrence. Regarding this announcement, Dr. Richard Kenney, Head of Clinical Development for TapImmune, stated, “We are pleased to complete enrollment in this study almost…
UroGen Pharma is a clinical-stage biopharmaceutical company focused on developing novel therapies designed to change the standard of care for urological pathologies with a focus on uro-oncology. They currently have an innovative and broad pipeline of product candidates that they believe can overcome the deficiencies of current treatment options for a variety of urological conditions. Currently, their focus is on uro-oncology. The lead product candidates in this pipeline, MitoGel and VesiGel, are proprietary formulations of the chemotherapy drug Mitomycin C, or MMC. MMC is a generic drug which is currently used off-label for urothelial cancer treatment. UroGen is developing their product…
Altor BioScience is a clinical-stage biopharmaceutical company developing novel immunotherapies for the treatment of cancer and viral infections, based on its engineered cytokine technology platforms. It was formed in 2002 by Dr. Hing C. Wong as a spin-off from Sunol Molecular Corporation, and is backed by leading venture capital funds, including Sanderling Ventures and TVM Capital. They have two proprietary technology platforms: the STAR™ platform and the IL-15 Superagonist platform. The immune system is the human body’s defense system against disease. Their STARTM and IL-15 technologies are based on the cytokines interleukin-2 and interleukin-15 and can jump start the immune…
Soligenix, Inc. (Nasdaq: SNGX), a late-stage biopharmaceutical company focused on developing and commercializing products to treat rare diseases where there is an unmet medical need, recently announced that its President and Chief Executive Officer, Christopher J. Schaber, PhD, is to deliver a corporate presentation at the 2017 Biotech & Money Inv€$tival Showcase in London, England on Tuesday, November 14 at 1:30 PM GMT. The event will take place at The Waldorf Hilton Hotel. Biotech and Money connects corporates to capital, and the Inv€$tival Showcase is the most direct way of showcasing the latest investable private and public life science opportunities…
TapImmune (TPIV), a clinical-stage immuno-oncology company specializing in the development of immunotherapies targeting women’s cancers has announced that it has amended the patient inclusion criteria for its Phase 2 clinical trial of their T-cell therapeutic peptide vaccine TPIV200 to focus on women with Stage III and IV ovarian cancer who are in remission following their first round of successful platinum-based chemotherapy. TapImmune has enrolled the first women under this amended study protocol, which increases the population of patients that can be addressed with TPIV 200 as a potential maintenance therapy designed to prevent disease recurrence. TPIV200 targets the folate receptor…